ausblenden:
Schlagwörter:
Bacteria/genetics
Bacterial Proteins/genetics
Gram-Negative Bacteria/genetics
*Type VI Secretion Systems/genetics
T6SS subtypes
comparative genomics
horizontal gene transfer
intraspecific variation
mobile genetic elements
presence/absence variation
type VI secretion system
Zusammenfassung:
The type VI secretion system (T6SS) is a molecular puncturing device that enables Gram-negative bacteria to kill competitors, manipulate host cells and take up nutrients. Who would want to miss such superpowers? Indeed, many studies show how widespread the secretion apparatus is among microbes. However, it is becoming evident that, on multiple taxonomic levels, from phyla to species and strains, some bacteria lack a T6SS. Here, we review who does and does not have a type VI secretion apparatus and speculate on the dynamic process of gaining and losing the secretion system to better understand its spread and distribution across the microbial world.
