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  Retrospective real-world pilot data on transcranial pulse stimulation in mild to severe Alzheimer's patients

Cont, C., Stute, N., Galli, A., Schulte, C., Logmin, K., Trenado, C., et al. (2022). Retrospective real-world pilot data on transcranial pulse stimulation in mild to severe Alzheimer's patients. Frontiers in Neurology, 13: 948204. doi:10.3389/fneur.2022.948204.

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Item Permalink: https://hdl.handle.net/21.11116/0000-000B-46DC-F Version Permalink: https://hdl.handle.net/21.11116/0000-000B-4DCB-B
Genre: Journal Article

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mus-22-tre-01-retrospective.pdf (Publisher version), 3MB
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Copyright © 2022 Cont, Stute, Galli, Schulte, Logmin, Trenado and Wojtecki. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
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 Creators:
Cont, Celine1, 2, Author
Stute, Nathalie1, Author
Galli, Anastasia1, Author
Schulte, Christina1, Author
Logmin, Kazimierz1, Author
Trenado, Carlos3, Author                 
Wojtecki, Lars1, 2, Author
Affiliations:
1Departmemt of Neurology and Neurorehabilitation, Hospital Zum Heiligen Geist, Academic Teaching Hospital of the Heinrich-Heine-University , Duesseldorf, Kempen, Germany, ou_persistent22              
2Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich-Heine-University Düsseldorf , Düsseldorf, Germany, ou_persistent22              
3Department of Music, Max Planck Institute for Empirical Aesthetics, Max Planck Society, ou_2421696              

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Free keywords: neuromodulation, transcranial pulse stimulation, Alzheimer's disease (AD), dementia, real-world data
 Abstract: Transcranial pulse stimulation (TPS) is a non-invasive neuromodulation therapy that uses short, repetitive shockwaves through a neuro-navigated device. Current research suggests that these pulses lead to a wide range of vascular, metabolic, and neurotrophic changes. This relatively new CE-marked treatment provided first promising results in a clinical pilot study for improving cognition in mild-to-moderate Alzheimer's. Data from other centers is lacking, so here we analyzed safety and pilot real-world short-term results of TPS from the first center in Germany. To gain information about effects in different stages, patients with not only mild but also moderate-to-severe Alzheimer's were analyzed.

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Language(s): eng - English
 Dates: 2022-05-192022-08-152022-09-14
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.3389/fneur.2022.948204
 Degree: -

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Title: Frontiers in Neurology
Source Genre: Journal
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Publ. Info: Lausanne, Switzerland : Frontiers Research Foundation
Pages: - Volume / Issue: 13 Sequence Number: 948204 Start / End Page: - Identifier: ISSN: 1664-2295
CoNE: https://pure.mpg.de/cone/journals/resource/1664-2295