ausblenden:
Schlagwörter:
ATP-Dependent Proteases/*metabolism
Bacteria/*enzymology
Biocatalysis
Eukaryotic Cells/enzymology
Mitochondria/*enzymology
Repressor Proteins/metabolism
Substrate Specificity
Zusammenfassung:
FtsH/AAA proteases comprise a distinct family of membrane-bound, ATP-dependent proteases present in eubacteria and eukaryotic cells, where they are confined to mitochondria and chloroplasts. Here, we will summarize versatile functions of AAA proteases within mitochondria, which ensure mitochondrial integrity and cell survival, acting both as quality control and processing enzymes.