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microbiome, GWAS, cospeciation, codiversification, phylosymbiosis, sirt5, sirt4, drosophila, mus musculus, shotgun metagenome sequencing, 16S rRNA sequencing, microbial DNA enrichment
Abstract:
All animals and plants are colonized by microorganisms, whereby different host species contain different microbial populations. These microbial communities form long-term relationships with their hosts. Understanding the genomic basis underlying these relationships provides insight into the possible coevolution between hosts and their microbiota. This thesis aims to contribute to a deeper understanding of the forces shaping the microbiome.