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  Tracking gene order provides a new perspective on intraspecific evolution in microbiotas

Enav, H., & Ley, R. (2024). Tracking gene order provides a new perspective on intraspecific evolution in microbiotas. Nature Biotechnology, Epub ahead. doi:10.1038/s41587-024-02277-1.

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Item Permalink: https://hdl.handle.net/21.11116/0000-000F-76D3-E Version Permalink: https://hdl.handle.net/21.11116/0000-000F-76D4-D
Genre: Journal Article

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https://www.nature.com/articles/s41587-024-02277-1.pdf (Publisher version)
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 Creators:
Enav, H1, Author                 
Ley, R1, Author                 
Affiliations:
1Department Microbiome Science, Max Planck Institute for Biology Tübingen, Max Planck Society, ou_3371684              

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 Abstract: We developed SynTracker, a tool to track conspecific microbial strains using genome synteny. SynTracker is sensitive to genomic structural variation but not to single-nucleotide polymorphisms (SNPs). Combining SynTracker with methods for tracking strains using SNP profiles, we were able to detect species evolving by accumulating predominantly SNPs or predominantly structural variants.

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 Dates: 2024-06
 Publication Status: Published online
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 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1038/s41587-024-02277-1
PMID: 38898180
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Title: Nature Biotechnology
  Abbreviation : Nat. Biotechnol.
Source Genre: Journal
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Publ. Info: New York : Gale Group Inc.
Pages: - Volume / Issue: Epub ahead Sequence Number: - Start / End Page: - Identifier: ISSN: 1087-0156
CoNE: https://pure.mpg.de/cone/journals/resource/954926980065