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  Lipid droplets: A dynamic organelle moves into focus.

Beller, M., Thiel, K., Thul, P. J., & Jäckle, H. (2010). Lipid droplets: A dynamic organelle moves into focus. FEBS Letters, 584(11), 2176-2182. doi:10.1016/j.febslet.2010.03.022.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0012-D57D-A Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0027-F26F-1
Genre: Journal Article

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 Creators:
Beller, M.1, Author              
Thiel, Katharina1, Author              
Thul, P. J.1, Author              
Jäckle, H.1, Author              
Affiliations:
1Department of Molecular Developmental Biology, MPI for biophysical chemistry, Max Planck Society, ou_578590              

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Free keywords: Lipid droplet; Organelle interaction; Endoplasmic reticulum; Vesicles
 Abstract: Lipid droplets (LDs) were perceived as static storage deposits, which passively participate in the energy homeostasis of both cells and entire organisms. However, this view has changed recently after the realization of a complex and highly dynamic LD proteome. The proteome contains key components of the fat mobilization system and proteins that suggest LD interactions with a variety of cell organelles, including the endoplasmic reticulum, mitochondria and peroxisomes. The study of LD cell biology, including cross-talk with other organelles, the trafficking of LDs in the cell and regulatory events involving the LD coat proteins is now on the verge of leaving its infancy and unfolds that LDs are highly dynamic cellular organelles.

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Language(s): eng - English
 Dates: 2010-06-03
 Publication Status: Published in print
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 Rev. Method: Peer
 Identifiers: eDoc: 478480
DOI: 10.1016/j.febslet.2010.03.022
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Title: FEBS Letters
Source Genre: Journal
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Pages: - Volume / Issue: 584 (11) Sequence Number: - Start / End Page: 2176 - 2182 Identifier: -