Novel effector function for an old receptor

Klein, R.

doi:10.1038/ncb0102-e11

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Novel effector function for an old receptor

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Klein, R.
Department: Molecular Neurobiology / Klein, MPI of Neurobiology, Max Planck Society;

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Klein, R. (2002). Novel effector function for an old receptor. Nature Cell Biology, 4(1), E11-E12. doi:10.1038/ncb0102-e11.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0012-238C-C

Abstract

Integrins are cell surface receptors for extracellular matrix proteins and, as such, regulate adhesive cell-matrix interactions. New findings indicate that the beta(4) integrin subunit can also function as a signalling effector for the activated receptor tyrosine kinase Met and enhance invasive growth independent of its adhesive role.