Correlation-based cross validation of PRESS, MEGA PRESS editing and 2D JPRESS 
at 3T

Dokumaci, AS; Zölch, N; Wyss, M; Fuchs, A; Boesoger, P; Henning, A

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Correlation-based cross validation of PRESS, MEGA PRESS editing and 2D JPRESS at 3T

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https://www.ismrm.org/12/tp_06.htm
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Dokumaci, A., Zölch, N., Wyss, M., Fuchs, A., Boesoger, P., & Henning, A. (2012). Correlation-based cross validation of PRESS, MEGA PRESS editing and 2D JPRESS at 3T. Poster presented at 20th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0013-B794-2

Abstract

Neurotransmitters and antioxidants such as N-acetyl-aspartate (NAA), glutamate (Glu), glutamine (Gln), gamma-aminobutyric acid (GABA), and glutathione (GSH) play an important role in psychiatric pathophysiologies. Their detection in vivo can be performed by the dedicated 1H MRS methods such as PRESS using different echo times, MEGA-PRESS, and 2D JPRESS at 3T. However, the best method to be used is unknown. Therefore, in this work these methods were applied on 40 healthy volunteers and in 4 different brain regions for cross validation. PRESS sequence with the shortest echo time and JPRESS sequence were found to be the best candidates for this purpose.