Personalized medicine: from genotypes and molecular phenotypes towards computed 
therapy

Stegle, O; Roth, FP; Morris, Q; Listgarten, J

doi:10.1142/9789814366496_0031

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Personalized medicine: from genotypes and molecular phenotypes towards computed therapy

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Stegle, O
Research Group Machine Learning and Computational Biology, Max Planck Institute for Intelligent Systems, Max Planck Society;

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Citation

Stegle, O., Roth, F., Morris, Q., & Listgarten, J. (2012). Personalized medicine: from genotypes and molecular phenotypes towards computed therapy. In R. Altman, A. Dunker, L. Hunter, T. Murray, & T. Klein (Eds.), Biocomputing 2012: Proceedings of the Pacific Symposium (pp. 323-326). Singapore: World Scientific Publishing.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0013-B886-9

Abstract

Joint genotyping and large-scale phenotyping of molecular traits are currently available for a number of important patient study cohorts and will soon become feasible in routine medical practice. These data are one component of several that are setting the stage for the development of personalized medicine, promising to yield better disease classification, enabling more specific treatment, and also allowing for improved preventive medical screening. This conference session explores statistical challenges and new opportunities that arise from application of genome-scale experimentation for personalized genomics and medicine.