Psychostimulant effect of synthetic dermorphin analog

Eshchenko, OV; Nikolskaia, KA; Deigin, VI; Iarova, EP

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Psychostimulant effect of synthetic dermorphin analog

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https://link.springer.com/content/pdf/10.1007/BF02447359.pdf
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Eshchenko, O., Nikolskaia, K., Deigin, V., & Iarova, E. (1998). Psychostimulant effect of synthetic dermorphin analog. Bulletin of Experimental Biology and Medicine, 126(3), 866-868.

引用: https://hdl.handle.net/11858/00-001M-0000-0013-E931-B

要旨

The effect of a dermorphin analog on learning was studied in a Wistar rat model of the complex food-seeking task. The preparation decreased the degree of anxiety in a dose-independent manner. In a dose of 50 μg/kg it increased the number of “well”-learning rats by intensifying the learning process in rats with initially suppressed cognitive activity. In a dose of 150 μg/kg, the opioid decreased the number of “well”-learning rats due to disturbance of motivation mechanisms, which was manifested in behavioral instability.