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Microscopic self-organization of enzymic reactions in small volumes

MPG-Autoren
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Hess,  Benno
Emeritus Group Prof. Dr. B. Hess, Max Planck Institute for Medical Research, Max Planck Society;

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Zitation

Mikhailov, A. S., & Hess, B. (1996). Microscopic self-organization of enzymic reactions in small volumes. Journal of Physical Chemistry, 100(49), 19059-19065. doi:10.1021/jp9616627.


Zitierlink: http://hdl.handle.net/11858/00-001M-0000-0019-A737-9
Zusammenfassung
Using an enzymic reaction with allosteric product activation as example, we show that allosterically regulated reactions in small volumes may develop strong microscopic correlations between individual molecular reaction events. Such correlations lead to coherent synchronous activity of the enzymic molecular population which is revealed in frequent periodic spiking of the reaction