Rapid Asymmetric Synthesis of Highly Functionalized Indanols via a 
Michael/Henry Organocascade with Submol% Squaramide Catalyst Loadings

Loh, Charles C. J.; Chauhan, Pankaj; Hack, Daniel; Lehmann, Christian W.; Enders, Dieter

doi:10.1002/adsc.201400499

アイテム詳細

登録内容を編集ファイル形式で保存

一時保存へ追加

タグ情報を表示リリース履歴を表示詳細要約

公開

学術論文

Rapid Asymmetric Synthesis of Highly Functionalized Indanols via a Michael/Henry Organocascade with Submol% Squaramide Catalyst Loadings

MPS-Authors

/persons/resource/persons58744

Lehmann, Christian W.
Service Department Lehmann (EMR), Max-Planck-Institut für Kohlenforschung, Max Planck Society;

External Resource

There are no locators available

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

フルテキスト (公開)

公開されているフルテキストはありません

付随資料 (公開)

There is no public supplementary material available

引用

Loh, C. C. J., Chauhan, P., Hack, D., Lehmann, C. W., & Enders, D. (2014). Rapid Asymmetric Synthesis of Highly Functionalized Indanols via a Michael/Henry Organocascade with Submol% Squaramide Catalyst Loadings. Advanced Synthesis & Catalysis, 356(14-15), 3181-3186. doi:10.1002/adsc.201400499.

引用: https://hdl.handle.net/11858/00-001M-0000-0024-BF60-B

要旨

An expedient asymmetric synthesis of
polyfunctionalized indanols bearing four contiguous
stereogenic centres, including a quarternary centre
through the use of sub-mol% amounts of a squaramide
catalyst within minutes is presented. A gramscale
experiment of this Michael/Henry organcascade
pushes the frontier of catalyst loading of organocascades
down to only 0.1 mol%, attaining
a TON of up to 910.