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Patent

Polysaccharide antigen-glycolipid conjugate vaccines

MPS-Authors
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Seeberger,  Peter H.
Peter H. Seeberger - Vaccine Development, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

/persons/resource/persons121895

Stallforth,  Pierre
Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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2156805.pdf
(Publisher version), 4MB

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Citation

Seeberger, P. H., Stallforth, P., De Libero, G., & Cavallari, M.(2013). Polysaccharide antigen-glycolipid conjugate vaccines.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0027-13B8-F
Abstract
The present invention relates to the field of synthesizing and biologically evaluating of a novel class of carbohydratebased vaccines. The new vaccines consist of a multi- modular structure which allows applying the vaccine to a whole variety of pathogenes. This method allows preparing vaccines against all pathogens expressing immunogenic carbohydrate antigens. As conjugation of antigenic carbohydrates to proteins is not required the conjugate vaccine is particularly heat stable. No refrigeration is required, a major drawback of protein-based vaccines.