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Journal Article

A trifluoromethylphenyl diazirine-based SecinH3 photoaffinity probe

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Citation

Albertoni, B., Hannam, J. S., Ackermann, D., Schmitz, A., & Famulok, M. (2012). A trifluoromethylphenyl diazirine-based SecinH3 photoaffinity probe. Chemical Communications, 48(9), 1272-4. doi:10.1039/c2cc16477a.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0028-641A-7
Abstract
The synthesis of a trifluoromethylphenyl diazirine photoaffinity probe of the cytohesin inhibitor SecinH3 is described. The probe exhibits improved labelling efficiency over a benzophenone-based probe and thus is more suitable for photoaffinity labelling in complex biological samples.