A trifluoromethylphenyl diazirine-based SecinH3 photoaffinity probe

Albertoni, B.; Hannam, J. S.; Ackermann, D.; Schmitz, A.; Famulok, M.

doi:10.1039/c2cc16477a

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A trifluoromethylphenyl diazirine-based SecinH3 photoaffinity probe

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http://www.ncbi.nlm.nih.gov/pubmed/22179571
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Citation

Albertoni, B., Hannam, J. S., Ackermann, D., Schmitz, A., & Famulok, M. (2012). A trifluoromethylphenyl diazirine-based SecinH3 photoaffinity probe. Chemical Communications, 48(9), 1272-4. doi:10.1039/c2cc16477a.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0028-641A-7

Abstract

The synthesis of a trifluoromethylphenyl diazirine photoaffinity probe of the cytohesin inhibitor SecinH3 is described. The probe exhibits improved labelling efficiency over a benzophenone-based probe and thus is more suitable for photoaffinity labelling in complex biological samples.