Deutsch
 
Hilfe Datenschutzhinweis Impressum
  DetailsucheBrowse

Datensatz

DATENSATZ AKTIONENEXPORT

Freigegeben

Zeitschriftenartikel

Synthesis of binary nanopatterns on hydrogels for initiating cellular responses

MPG-Autoren
/persons/resource/persons118734

Guasch,  Judit
Cellular Biophysics, Max Planck Institute for Medical Research, Max Planck Society;
Biophysical Chemistry, Institute of Physical Chemistry, University of Heidelberg, 69120 Heidelberg, Germany;

/persons/resource/persons192061

Diemer,  Jennifer
Cellular Biophysics, Max Planck Institute for Medical Research, Max Planck Society;
Biophysical Chemistry, Institute of Physical Chemistry, University of Heidelberg, 69120 Heidelberg, Germany;

/persons/resource/persons76135

Spatz,  Joachim P.
Cellular Biophysics, Max Planck Institute for Medical Research, Max Planck Society;
Biophysical Chemistry, Institute of Physical Chemistry, University of Heidelberg, 69120 Heidelberg, Germany;

Volltexte (beschränkter Zugriff)
Für Ihren IP-Bereich sind aktuell keine Volltexte freigegeben.
Volltexte (frei zugänglich)
Es sind keine frei zugänglichen Volltexte in PuRe verfügbar
Ergänzendes Material (frei zugänglich)
Es sind keine frei zugänglichen Ergänzenden Materialien verfügbar
Zitation

Guasch, J., Diemer, J., Riahinezhad, H., Neubauer, S., Kessler, H., & Spatz, J. P. (2016). Synthesis of binary nanopatterns on hydrogels for initiating cellular responses. Chemistry of Materials, 28(6), 1806-1815. doi:10.1021/acs.chemmater.5b04910.


Zitierlink: https://hdl.handle.net/11858/00-001M-0000-002A-1BEF-C
Zusammenfassung
We describe the synthesis of binary nanostructures consisting of PEG hydrogels decorated with arrays of AuNPs and TiO2NPs, and their orthogonal functionalization with various peptides. These ligands are able to promote or elude cell adhesion through integrins, a family of transmembrane receptors that connect cells with the extracellular matrix (ECM) or other cells. The different cell adhesion behaviors observed depending on the peptides used, proved the functionality of such binary nanopatterns, which we expect to find applications not only in tissue engineering but also in smart cell culture systems and biosensors.