Anthrax toxin rafts into cells

Kurzchalia, T.

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Anthrax toxin rafts into cells

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Kurzchalia, T.
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Kurzchalia, T. (2003). Anthrax toxin rafts into cells. Journal of Cell Biology, 160(3), 295-296.

Cite as: https://hdl.handle.net/21.11116/0000-0001-12A1-4

Abstract

Anthrax toxin binds to a plasma membrane receptor and after endocytosis exerts its deadly effects on the cell. Until now, however, the mechanism of initial toxin uptake was unknown. In this issue, Abrami et al. (2003) demonstrate that toxin oligomerization clusters the anthrax receptor into lipid rafts and this complex is internalized via the clathrin-dependent pathway.