Relaxation-compensated multi-pool CEST signal at 7T MRI of WHO IV gliomas is 
dependent on the anatomic localization

Dreher, C; Oberhollenzer, J; Windschuh, J; Meissner, J-E; Sahm, F; Bendszus, M; Unterberg, A; Wick, W; Bachert, P; Ladd, ME; Schlemmer, H-P; Zaiss, M; Radbruch, A; Paech, D

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Poster

Relaxation-compensated multi-pool CEST signal at 7T MRI of WHO IV gliomas is dependent on the anatomic localization

MPS-Authors

/persons/resource/persons214560

Zaiss, M
Max Planck Institute for Biological Cybernetics, Max Planck Society;
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

External Resource

Link
(Abstract)

https://www.ismrm.org/18/Electronic_Posters.pdf
(Abstract)

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Dreher, C., Oberhollenzer, J., Windschuh, J., Meissner, J.-E., Sahm, F., Bendszus, M., et al. (2018). Relaxation-compensated multi-pool CEST signal at 7T MRI of WHO IV gliomas is dependent on the anatomic localization. Poster presented at Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France.

Cite as: https://hdl.handle.net/21.11116/0000-0001-7DCC-E

Abstract

As patients with WHO IV° gliomas are still having a dismal prognosis, further tumor characterization is needed. With prognosis and histopathological parameters being dependent on tumor localization, and Chemical-Exchange-Saturation-Transfer(CEST) MRI at 7T being one of the latest advances in tumor imaging, we have prospectively evaluated CEST signals in 21 patients. Amide CEST and ADC parameters are significantly different with regard to brain hemispheres and correlating. CEST NOE(Nuclear Overhauser-Effect) is not different with regard to brain hemispheres, but in case of contact to the subventricular zone, which is accompanied by worse prognosis. NOE is possibly showing complementary information to Amide CEST.