A sex-inducing pheromone triggers cell cycle arrest and mate attraction in the 
diatom Seminavis robusta

Moeys, Sara; Frenkel, Johannes; Lembke, Christine; Gillard, Jeroen T. F.; Devos, Valerie; den Berge, Koen Van; Bouillon, Barbara; Huysman, Marie J. J.; Decker, Sam De; Scharf, Julia; Bones, Atle; Brembu, Tore; Winge, Per; Sabbe, Koen; Vuylsteke, Marnik; Clement, Lieven; Veylder, Lieven De; Pohnert, Georg; Vyverman, Wim

doi:10.1038/srep19252

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学術論文

A sex-inducing pheromone triggers cell cycle arrest and mate attraction in the diatom Seminavis robusta

MPS-Authors

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Frenkel, Johannes
IMPRS on Ecological Interactions, MPI for Chemical Ecology, Max Planck Society;

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http://dx.doi.org/10.1038/srep19252
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IMPRS005.pdf
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IMPRS005s1.pdf
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IMPRS005s2.xls
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引用

Moeys, S., Frenkel, J., Lembke, C., Gillard, J. T. F., Devos, V., den Berge, K. V., Bouillon, B., Huysman, M. J. J., Decker, S. D., Scharf, J., Bones, A., Brembu, T., Winge, P., Sabbe, K., Vuylsteke, M., Clement, L., Veylder, L. D., Pohnert, G., & Vyverman, W. (2016). A sex-inducing pheromone triggers cell cycle arrest and mate attraction in the diatom Seminavis robusta. Scientific Reports, 6:. doi:10.1038/srep19252.

引用: https://hdl.handle.net/21.11116/0000-0003-09A8-6

要旨

Although sexual reproduction is believed to play a major role in the high diversification rates and species richness of diatoms, a mechanistic understanding of diatom life cycle control is virtually lacking. Diatom sexual signalling is controlled by a complex, yet largely unknown, pheromone system. Here, a sex-inducing pheromone (SIP+) of the benthic pennate diatom Seminavis robusta was identified by comparative metabolomics, subsequently purified, and physicochemically characterized. Transcriptome analysis revealed that SIP+ triggers the switch from mitosis-to-meiosis in the opposing mating type, coupled with the transcriptional induction of proline biosynthesis genes, and the release of the proline-derived attraction pheromone. The induction of cell cycle arrest by a pheromone, chemically distinct from the one used to attract the opposite mating type, highlights the existence of a sophisticated mechanism to increase chances of mate finding, while keeping the metabolic losses associated with the release of an attraction pheromone to a minimum.