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Journal Article

Asymmetric inhibition by phlorizin of halide movements across the red blood cell membrane

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Lepke,  Sigrid
Department of Cell Physiology, Max Planck Institute of Biophysics, Max Planck Society;

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Passow,  Hermann
Department of Cell Physiology, Max Planck Institute of Biophysics, Max Planck Society;

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Citation

Schnell, K., Gerhardt, S., Lepke, S., & Passow, H. (1973). Asymmetric inhibition by phlorizin of halide movements across the red blood cell membrane. Biochimica et Biophysica Acta-Biomembranes, 318(3), 474-477. doi:10.1016/0005-2736(73)90213-7.


Cite as: https://hdl.handle.net/21.11116/0000-0009-E43C-3
Abstract
Using human red cell ghosts, it was shown that external phlorizin inhibits Cl and I equilibrium exchange. Internal phlorizin has little effect on I exchange and no detectable effect on Cl exchange. This asymmetry is similar to that observed with the much more slowly exchanging SO42− and different from that of sugars like l-arabinose or d-xylose which are inhibited by phlorizin from either surface.