English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT

Released

Journal Article

Simulation of waves in calcium models with 3D spherical geometry

MPS-Authors
/persons/resource/persons21660

Ipsen,  Mads
Physical Chemistry, Fritz Haber Institute, Max Planck Society;

External Ressource
No external resources are shared
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available
Citation

Hunding, A., & Ipsen, M. (2003). Simulation of waves in calcium models with 3D spherical geometry. Mathematical Biosciences, 182(1), 45-66. doi:10.1016/S0025-5564(02)00179-7.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0011-1116-0
Abstract
Waves of calcium ions are present in fertilized eggs of many species. Models for pulse and tidal wave propagation have usually been studied in one or two spatial coordinates only. We examine in three spatial coordinates some established models, based on Ca2+-induced Ca2+-release from both (assumed) continuously or heterogeneously distributed stores of endoplasmic reticulum (ER) through channels activated by inositol triphosphate (IP3). With continuous IP3 distribution decreasing radially towards the interior, we obtain concave pulse shapes for waves penetrating the interior. Concave waves are also recorded in systems with ER confined to distributions of small spheres (microdomains) inside the cell, which we simulate for front waves (tides) in bistable systems.