Deutsch
 
Hilfe Datenschutzhinweis Impressum
  DetailsucheBrowse

Datensatz

DATENSATZ AKTIONENEXPORT

Freigegeben

Poster

Understanding signal specificity in fMRI: bSSFP vs. GRE-EPI signal dependence on cortical orientation to B0 at 9.4 Tesla

MPG-Autoren
/persons/resource/persons272752

Ramadan,  D
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons192600

Bause,  J       
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons238878

Mueller,  S       
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons215985

Bosch,  D       
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

Externe Ressourcen
Volltexte (beschränkter Zugriff)
Für Ihren IP-Bereich sind aktuell keine Volltexte freigegeben.
Volltexte (frei zugänglich)
Es sind keine frei zugänglichen Volltexte in PuRe verfügbar
Ergänzendes Material (frei zugänglich)
Es sind keine frei zugänglichen Ergänzenden Materialien verfügbar
Zitation

Ramadan, D., Bause, J., Mueller, S., Bosch, D., Stirnberg, R., Ehses, P., et al. (2024). Understanding signal specificity in fMRI: bSSFP vs. GRE-EPI signal dependence on cortical orientation to B0 at 9.4 Tesla. Poster presented at ISMRM & ISMRT Annual Meeting & Exhibition 2024, Singapore.


Zitierlink: https://hdl.handle.net/21.11116/0000-000F-396F-6
Zusammenfassung
Motivation: GRE-EPI, the most widely used sequence for BOLD fMRI, is highly biased towards large draining veins that follow the cortical curvature and influence the surrounding magnetic field in an orientation-dependent manner increasing with field strength. Goal(s): This work aims to investigate large vein biases resulting in cortical orientation-dependent signal variations in GRE-EPI and bSSFP resting-state fMRI signals. Approach: We compared 2D and 3D GRE-EPI with 3D bSSFP rs-fMRI signal fluctuations in their dependence on the cortical orientation to B in five subjects at 9.4 Tesla. Results: Unlike GRE-EPI, intra- and inter-subject comparisons revealed no dependence of bSSFP on the cortical orientation to B . Impact: Fluctuations in the GRE-EPI signal are highly dependent on the cortical orientation and depth. This was not observed with bSSFP, demonstrating the potentially higher specificity of bSSFP for smaller veins, closer to brain activation at field strengths ≥ 7 Tesla.