Researcher Portfolio

 
   

Prof. Dr. Erb, Tobias J.

Cellular Operating Systems, Department of Biochemistry and Synthetic Metabolism, Max Planck Institute for Terrestrial Microbiology, Max Planck Society, Center for Synthetic Microbiology (SYNMIKRO), Philipps University of Marburg, Marburg, Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zurich, Zurich, Switzerland, Mikrobiologie, Institut für Biologie II, Albert-Ludwigs-Universität Freiburg, Freiburg, The Ohio State University, Columbus, Ohio, United States, Understanding and Building Metabolism, Department of Biochemistry and Synthetic Metabolism, Max Planck Institute for Terrestrial Microbiology, Max Planck Society, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States  

 

Researcher Profile

 
Position: Director (Understanding and Building Metabolism, Department of Biochemistry and Synthetic Metabolism, Max Planck Institute for Terrestrial Microbiology, Max Planck Society)
Position: Center for Synthetic Microbiology (SYNMIKRO), Philipps University of Marburg, Marburg
Position: Mikrobiologie, Institut für Biologie II, Albert-Ludwigs-Universität Freiburg, Freiburg
Position: Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zurich, Zurich, Switzerland
Position: University of Illinois at Urbana-Champaign, Urbana, Illinois, United States
Position: The Ohio State University, Columbus, Ohio, United States
Position: Director (Cellular Operating Systems, Department of Biochemistry and Synthetic Metabolism, Max Planck Institute for Terrestrial Microbiology, Max Planck Society)
Researcher ID: https://pure.mpg.de/cone/persons/resource/persons254247

External references

 

Publications

 
  (1 - 25 of 166)
 : Rasor, B. J., & Erb, T. J. (2025). Cell-free systems to mimic and expand metabolism. ACS Synthetic Biology. doi:10.1021/acssynbio.4c00729. [PubMan] : Schulz, L., Zarzycki, J., Steinchen, W., Hochberg, G. K. A., & Erb, T. J. (2025). Layered entrenchment maintains essentiality in the evolution of Form I Rubisco complexes. The EMBO Journal, 44, 269-280. doi:10.1038/s44318-024-00311-1. [PubMan] : Abil, Z., Giaveri, S., Erb, T. J., & Rothschild, L. J. (2024). Integrating metabolism and evolution towards the realization of synthetic life. Nature Reviews Bioengineering. doi:10.1038/s44222-024-00267-1. [PubMan] : Schulz-Mirbach, H., Wichmann, P., Satanowski, A., Meusel, H., Wu, T., Nattermann, M., Burgener, S., Paczia, N., Bar-Even, A., & Erb, T. J. (2024). New-to-nature CO2-dependent acetyl-CoA assimilation enabled by an engineered B12-dependent acyl-CoA mutase. Nature Communications, 15: 10235. doi:10.1038/s41467-024-53762-9. [PubMan] : He, H., Gómez-Coronado, P. A., Zarzycki, J., Barthel, S., Kahnt, J., Claus, P., Klein, M., Klose, M., de Crécy-Lagard, V., Schindler, D., Paczia, N., Glatter, T., & Erb, T. J. (2024). Adaptive laboratory evolution recruits the promiscuity of succinate semialdehyde dehydrogenase to repair different metabolic deficiencies. Nature Communications, 15(1): 8898. doi:10.1038/s41467-024-53156-x. [PubMan] : Barthel, S., Brenker, L., Diehl, C., Bohra, N., Giaveri, S., Paczia, N., & Erb, T. J. (2024). in vitro transcription-based biosensing of glycolate for prototyping of a complex enzyme cascade. Synthetic Biology, ysae013. doi:10.1093/synbio/ysae013. [PubMan] : Orsi, E., Schulz-Mirbach, H., Cotton, C. A., Satanowski, A., Petri, H., Arnold, S. L., Grabarczyk, N., Verbakel, R., Jensen, K. S., Donati, S., Paczia, N., Glatter, T., Küffner, A. M., Chotel, T., Schillmueller, F., De Maria, A., He, H., Lindner, S. N., Noor, E., Bar-Even, A., Erb, T. J., & Nikel, P. I. (2024). Expanding the biotechnological scope of metabolic sensors through computation-aided designs. bioRxiv: the preprint server for biology, 2024.08.23.609350. [PubMan] : Schulz-Mirbach, H., Krüsemann, J. L., Andreadaki, T., Nerlich, J. N., Mavrothalassiti, E., Boecker, S., Schneider, P., Weresow, M., Abdelwahab, O., Paczia, N., Dronsella, B., Erb, T. J., Bar-Even, A., Klamt, S., & Lindner, S. N. (2024). Engineering new-to-nature biochemical conversions by combining fermentative metabolism with respiratory modules. Nature Communications, 15(1): 6725. doi:10.1038/s41467-024-51029-x. [PubMan] : Schann, K., Bakker, J., Boinot, M., Kuschel, P., He, H., Nattermann, M., Paczia, N., Erb, T. J., Bar-Even, A., & Wenk, S. (2024). Design, construction and optimization of formaldehyde growth biosensors with broad application in biotechnology. Microbial Biotechnology, 17(7): e14527. doi:10.1111/1751-7915.14527. [PubMan] : Kim, Y., Lee, S. H., Gade, P., Nattermann, M., Maltseva, N., Endres, M., Chen, J., Wichmann, P., Hu, Y., Marchal, D. G., Yoshikuni, Y., Erb, T. J., Gonzalez, R., Michalska, K., & Joachimiak, A. (2024). Revealing reaction intermediates in one-carbon elongation by thiamine diphosphate/CoA-dependent enzyme family. Communications Chemistry, 7(1). doi:10.1038/s42004-024-01242-y. [PubMan] : Giaveri, S., Bohra, N., Diehl, C., Yang, H. Y., Ballinger, M., Paczia, N., Glatter, T., & Erb, T. J. (2024). Integrated translation and metabolism in a partially self-synthesizing biochemical network. Science, 385(6705), 174-178. doi:10.1126/science.adn3856. [PubMan] : Schada v. Borzyskowsi, L., Lucas, H., Kremer, K., Barthel, S., Pommerenke, B., Glatter, T., Paczia, N., Erhard, B., & Erb, T. J. (2024). Multiple levels of transcriptional regulation control glycolate metabolism in Paracoccus denitrificans. mBio, 15(8): e0152424. doi:10.1128/mbio.01524-24. [PubMan] : Küffner, A. M., Pommerenke, B., Kley, L., Ng, J. Z. Y., Prinz, S., Tinzl-Zechner, M., Claus, P., Paczia, N., Zarzycki, J., Hochberg, G. K. A., & Erb, T. J. (2024). Bottom-up reconstruction of minimal pyrenoids provides insights into the evolution and mechanisms of carbon concentration by EPYC1 proteins. bioRxiv: the preprint server for biology, 2024.06.28.601168. [PubMan] : Inckemann, R., Chotel, T., Brinkmann, C. K., Burgis, M., Andreas, L., Baumann, J., Sharma, P., Klose, M., Barret, J., Ries, F., Paczia, N., Glatter, T., Mackinder, L., Willmund, F., & Erb, T. J. (2024). Advancing chloroplast synthetic biology through high-throughput plastome engineering of Chlamydomonas reinhardtii. bioRxiv: the preprint server for biology, 2024.05.08.593163. [PubMan] : Barthel, S., Brenker, L., Diehl, C., Bohra, N., Giaveri, S., Paczia, N., & Erb, T. J. (2024). In vitro transcription-based biosensing of glycolate for prototyping of a complex enzyme cascade. bioRxiv: the preprint server for biology, 2024.04.26.591264. [PubMan] : Sendker, F. L., Lo, Y. K., Heimerl, T., Bohn, S., Persson, L. J., Mais, C.-N., Sadowska, W., Paczia, N., Nußbaum, E., del Carmen Sánchez Olmos, M., Forchhammer, K., Schindler, D., Erb, T. J., Benesch, J. L. P., Marklund, E. G., Bange, G., Schuller, J. M., & Hochberg, G. K. A. (2024). Emergence of fractal geometries in the evolution of a metabolic enzyme. Nature, 628(8009), 894-900. doi:10.1038/s41586-024-07287-2. [PubMan] : Gomez, A., Tinzl, M., Stoffel, G. M. M., Westedt, H., Grubmüller, H., Erb, T. J., Vöhringer-Martinez, E., & Stripp, S. T. (2024). Infrared spectroscopy reveals metal-independent carbonic anhydrase activity in crotonyl-CoA carboxylase/reductase. Chemical Science, 15(13), 4960-4968. doi:10.1039/D3SC04208A. [PubMan] : Joachimiak, A., Kim, Y., Lee, S. H., Gade, P., Nattermann, M., Maltseva, N., Endres, M., Chen, J., Wichmann, P., Hu, Y., Marchal, D. G., Yoshikuni, Y., Erb, T. J., Gonzalez, R., & Michalska, K. (2024). Revealing reaction intermediates in one-carbon elongation ThDP/CoA dependent enzyme family. Research Square. [PubMan] : Schada v. Borzyskowsi, L., Hermann, L., Kremer, K., Barthel, S., Pommerenke, B., Glatter, T., Paczia, N., Bremer, E., & Erb, T. J. (2024). Multiple levels of transcriptional regulation control glycolate metabolism in Paracoccus denitrificans. bioRxiv: the preprint server for biology, 2024.03.11.584432. [PubMan] : Schulz, L., Zarzycki, J., Steinchen, W., Hochberg, G. K. A., & Erb, T. J. (2024). Layered entrenchment maintains essentiality in protein-protein interactions. bioRxiv: the preprint server for biology, 2024.01.18.576253. [PubMan] : Schmidt, F. V., Schulz, L., Zarzycki, J., Prinz, S., Oehlmann, N. N., Erb, T. J., & Rebelein, J. G. (2024). Structural insights into the iron nitrogenase complex. Nature Structural & Molecular Biology, 31(1), 150-158. doi:10.1038/s41594-023-01124-2. [PubMan] : Erb, T. J. (2024). Bringing Photosynthesis 2.0 to Life. In U. A. Betz (Ed.), Curious Future Insight (pp. 49-64). Springer, Cham. [PubMan] : Nattermann, M., Wenk, S., Pfister, P., He, H., Lee, S., Szymanski, W., Guntermann, N., Zhu, F., Nickel, L., Wallner, C., Zarzycki, J., Paczia, N., Gaißert, N., Franciò, G., Leitner, W., Gonzalez, R., & Erb, T. J. (2023). Engineering a new-to-nature cascade for phosphate-dependent formate to formaldehyde conversion in vitro and in vivo. Nature Communications, 14(1): 2682. doi:10.1038/s41467-023-38072-w. [PubMan] : Gomez, A., Erb, T. J., Grubmüller, H., & Vöhringer-Martinez, E. (2023). Conformational dynamics of the most efficient carboxylase contributes to efficient CO2 fixation. Journal of Chemical Information and Modeling, 63(24), 7807-7815. doi:10.1021/acs.jcim.3c01447. [PubMan] : Giaveri, S., Bohra, N., Diehl, C., Ballinger, M., Paczia, N., Glatter, T., & Erb, T. J. (2023). An interdependent metabolic and genetic network shows emergent properties in vitro. bioRxiv: the preprint server for biology, 2023.11.26.568713. [PubMan]