Researcher Portfolio
Hoopes, J. Todd
Fässler, Reinhard / Molecular Medicine, Max Planck Institute of Biochemistry, Max Planck Society
Researcher Profile
Position: Fässler, Reinhard / Molecular Medicine, Max Planck Institute of Biochemistry, Max Planck Society
Researcher ID: https://pure.mpg.de/cone/persons/resource/persons78130
Publications
(1 - 25 of 35)
: Helmbrecht, N., Lackner, M., Maricic, T., & Pääbo, S. (2024). The modern human aryl hydrocarbon receptor is more active when ancestralized by genome editing. Proceedings of the National Academy of Sciences, 121(22): e2402159121. doi:10.1073/pnas.2402159121. [PubMan] : The COVID-19 Host Genetics Initiative, including authors, Zeberg, H., & Maricic, T. (2023). A second update on mapping the human genetic architecture of COVID-19. Nature, 621, E7-E26. doi:10.1038/s41586-023-06355-3. [PubMan] : Riesenberg, S., Kanis, P., Macak, D., Wollny, D., Düsterhöft, D., Kowalewski, J., Helmbrecht, N., Maricic, T., & Pääbo, S. (2023). Efficient high-precision homology-directed repair-dependent genome editing by HDRobust. Nature Methods, 20, 1388-1399. doi:10.1038/s41592-023-01949-1. [PubMan] : Pinson, A., Xing, L., Namba, T., Kalebic, N., Peters, J., Oegema, C. E., Traikov, S., Reppe, K., Riesenberg, S., Maricic, T., Derihaci, R., Wimberger, P., Pääbo, S., & Huttner, W. B. (2022). Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals. Science, 377(6611): eabl6422, pp. 1170. doi:10.1126/science.abl6422. [PubMan] : COVID-19 Genetics Initiative, including authors, Zeberg, H., & Maricic, T. (2022). A first update on mapping the human genetic architecture of COVID-19. Nature, 608, E1-E10. doi:10.1038/s41586-022-04826-7. [PubMan] : Mora-Bermúdez, F., Kanis, P., Macak, D., Peters, J., Naumann, R., Xing, L., Sarov, M., Winkler, S., Oegema, C. E., Haffner, C., Wimberger, P., Riesenberg, S., Maricic, T., Huttner, W. B., & Pääbo, S. (2022). Longer metaphase and fewer chromosome segregation errors in modern human than Neanderthal brain development. Science Advances, 8: eabn7702. doi:10.1126/sciadv.abn7702. [PubMan] : Riesenberg, S., Helmbrecht, N., Kanis, P., Maricic, T., & Pääbo, S. (2022). Improved gRNA secondary structures allow editing of target sites resistant to CRISPR-Cas9 cleavage. Nature Communications, 13: 489. doi:10.1038/s41467-022-28137-7. [PubMan] : Stepanova, V., Moczulska, K., Vacano, G. N., Kurochkin, I., Ju, X.-C., Riesenberg, S., Macak, D., Maricic, T., Dombrowski, L., Schörnig, M., Anastassiadis, K., Baker, O., Naumann, R., Khrameeva, E., Vanushkina, A., Stekolschikova, E., Egorova, A., Nkatchev, A., Mazzarino, R., Duval, N., Zubkov, D., Giavalisco, P., Wilkinson, T. G., Patterson, D., Khaitovich, P., & Pääbo, S. (2021). Reduced purine biosynthesis in humans after their divergence from Neandertals. eLife, 10: e58741. doi:10.7554/eLife.58741. [PubMan] : Bokelmann, L., Nickel, O., Maricic, T., Pääbo, S., Meyer, M., Borte, S., & Riesenberg, S. (2021). Point-of-care bulk testing for SARS-CoV-2 by combining hybridization capture with improved colorimetric LAMP. Nature Communications, 12(1): 1467. doi:10.1038/s41467-021-21627-0. [PubMan] : Maricic, T., Helmbrecht, N., Riesenberg, S., Macak, D., Kanis, P., Lackner, M., Pugach-Matveeva, A. D., & Pääbo, S. (2021). Comment on “Reintroduction of the archaic variant of NOVA1 in cortical organoids alters neurodevelopment”. Science, 374(6565), 269. doi:10.1126/science.abi6060. [PubMan] : Suchý, T., Kaczmarek, I., Maricic, T., Zieschang, C., Schöneberg, T., Thor, D., & Liebscher, I. (2021). Evaluating the feasibility of Cas9 overexpression in 3T3-L1 cells for generation of genetic knock-out adipocyte cell lines. Adipocyte, 10(1), 631-645. doi:10.1080/21623945.2021.1990480. [PubMan] : Maricic, T., Nickel, O., Ayinuer-Petri, A., Essel, E., Gansauge, M.-T., Kanis, P., Macak, D., Riesenberg, S., Bokelmann, L., Zeberg, H., Meyer, M., Borte, S., & Pääbo, S. (2020). A direct RT-qPCR approach to test large numbers of individuals for SARS-CoV-2. PLoS One, 15(12): e0244824. doi:10.1371/journal.pone.0244824. [PubMan] : Zeberg, H., Dannemann, M., Sahlholm, K., Tsuo, K., Maricic, T., Wiebe, V., Hevers, W., Robinson, H. P., Kelso, J., & Pääbo, S. (2020). A Neandertal sodium channel increases pain sensitivity in present-day humans. Current Biology, 30(17), 3465-3469. doi:10.1016/j.cub.2020.06.045. [PubMan] : Riesenberg, S., Chintalapati, M., Macak, D., Kanis, P., Maricic, T., & Pääbo, S. (2019). Simultaneous precise editing of multiple genes in human cells. Nucleic Acids Research, 47(19): e116. doi:10.1093/nar/gkz669. [PubMan] : Riesenberg, S., & Maricic, T. (2018). Targeting repair pathways with small molecules increases precise genome editing in pluripotent stem cells. Nature Communications, 9: 2164. doi:10.1038/s41467-018-04609-7. [PubMan] : Prüfer, K., Filippo, C. d., Grote, S., Mafessoni, F., Korlevic, P., Hajdinjak, M., Vernot, B., Skov, L., Hsieh, P., Peyrégne, S., Reher, D., Hopfe, C., Nagel, S., Maricic, T., Fu, Q., Theunert, C., Rogers, R., Skoglund, P., Chintalapati, M., Dannemann, M., Nelson, B. J., Key, F. M., Rudan, P., Kucan, Ž., Gušic, I., Golovanova, L. V., Doronichev, V. B., Patterson, N., Reich, D., Eichler, E. E., Slatkin, M., Schierup, M. H., Andrés, A. M., Kelso, J., Meyer, M., & Pääbo, S. (2017). A high-coverage Neandertal genome from Vindija Cave in Croatia. Science, 358(6363), 655-658. doi:10.1126/science.aao1887. [PubMan] : Mora-Bermúdez, F., Badsha, F., Kanton, S., Camp, J. G., Vernot, B., Köhler, K., Voigt, B., Okita, K., Maricic, T., He, Z., Lachmann, R., Pääbo, S., Treutlein, B., & Huttner, W. B. (2016). Differences and similarities between human and chimpanzee neural progenitors during cerebral cortex development. eLife, e18683. doi:10.7554/eLife.18683. [PubMan] : Renaud, G., Stenzel, U., Maricic, T., Wiebe, V., & Kelso, J. (2015). deML: Robust demultiplexing of Illumina sequences using a likelihood-based approach. Bioinformatics, 31(5), 770-772. doi: 10.1093/bioinformatics/btu719. [PubMan] : Maricic, T., Günther, V., Georgiev, O., Gehre, S., Curlin, M., Schreiweis, C., Naumann, R., Burbano, H. A., Meyer, M., Lalueza-Fox, C., de la Rasilla, M., Rosas, A., Gajovic, S., Kelso, J., Enard, W., Schaffner, W., & Pääbo, S. (2013). A recent evolutionary change affects a regulatory element in the human FOXP2 gene. Molecular Biology and Evolution, 30(4), 844-852. doi:10.1093/molbev/mss271. [PubMan] : Burbano, H. A., Green, R. E., Maricic, T., Lalueza-Fox, C., de la Rasilla, M., Rosas, A., Kelso, J., Pollard, K. S., Lachmann, M., & Pääbo, S. (2012). Analysis of human accelerated DNA regions using archaic hominin genomes. PLoS One, 7(3): e32877. doi:10.1371/journal.pone.0032877. [PubMan] : Maricic, T. (2012). Development of methods for high-throughput DNA sequencing of the Neandertal genome. PhD Thesis, Universität, Leipzig. [PubMan] : Krause, J. *., Briggs, A. W., Kircher, M., Maricic, T., Zwyns, N., Derevianko, A. P., & Pääbo, S. (2010). A complete mtDNA genome of an early modern human from Kostenki, Russia. Current Biology, 20(3), 231-236. doi:10.1016/j.cub.2009.11.068. [PubMan] : Reich, D., Green, R. E., Kircher, M., Krause, J., Patterson, N., Durand, E. Y., Viola, B., Briggs, A. W., Stenzel, U., Johnson, P. L. F., Maricic, T., Good, J. M., Marques-Bonet, T., Alkan, C., Fu, Q., Mallick, S., Li, H., Meyer, M., Eichler, E. E., Stoneking, M., Richards, M., Talamo, S., Shunkov, M. V., Derevianko, A. P., Hublin, J.-J., Kelso, J., Slatkin, M., & Pääbo, S. (2010). Genetic history of an archaic hominin group from Denisova Cave in Siberia. Nature, 468(7327), 1053-1060. doi:10.1038/nature09710. [PubMan] : Burbano, H. A., Hodges, E., Green, R. E., Briggs, A. W., Krause, J., Meyer, M., Good, J. M., Maricic, T., Johnson, P. L. F., Xuan, Z., Rooks, M., Bhattacharjee, A., Brizuela, L., Albert, F. W., Rasilla, M. d. l., Fortea, J., Rosas, A., Lachmann, M., Hannon, G. J., & Pääbo, S. (2010). Targeted investigation of the Neandertal genome by array-based sequence capture. Science, 328(5979), 723-725. doi:10.1126/science.1188046. [PubMan] : Maricic, T., Whitten, M., & Pääbo, S. (2010). Multiplexed DNA sequence capture of mitochondrial genomes using PCR products. PLoS ONE, 5(11): e14004, pp. 1-5. doi:10.1371/journal.pone.0014004. [PubMan]